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| 中文名称 | 瑞舒伐他汀钙 |
|---|---|
| 中文别名 | 罗苏伐他汀钙;瑞舒伐他汀钙;罗舒伐他汀钙;超级他汀钙;(3R,5S,6E)-7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰胺基)-5-嘧啶]-3,5-二羟基-6-庚烯酸钙;罗苏伐他汀钙 GMP;(+)-双{7-[4-(4-氟苯基)-6-(1-甲基乙基)-2-[甲基(甲磺酰基)氨基]-5-嘧啶基]-3R,5S-二羟基-6（E）-庚烯酸}钙;Rosuvastatin Calcium 瑞舒伐他汀钙;甲磺酸西地那非;罗苏伐他汀钙（超级他汀钙）;罗苏伐他汀钙杂质;罗素伐他汀钙;瑞舒伐他汀-D3钙盐;瑞舒伐他汀钙 国药准字;瑞舒伐他汀钙盐;瑞苏伐他汀钙;超级他汀钙 罗素伐他汀钙;罗苏伐他汀钙 瑞舒伐他汀钙;罗素伐他丁钙;罗舒伐他汀;瑞舒伐他汀;罗伐他汀钙;瑞舒代他汀钙;超级他汀钙盐;瑞舒伐他汀钙(对照品) |
| 英文名称 | S-4522; S 4522; S4522; ZD 4522; ZD-4522; ZD4522; ZD 4522 calcium salt;Rosuvastatin hemicalcium; ZD 4522 Calcium;CRESTOR;Rosuvastatin Calcium Salt |
| 英文别名 | ROSUVASTATIN CALCIUM;MSDH-C;Rosuvastatin (as Ca salt);Rosuvastatin Calcium (ZD 4522 Calcium, Crestor®, Zyrova ®);Rosuvastatin Calcium Salt;(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt;Crestor;Fortius;Rostar;Rosuvastatin Hemicalcium;S 4522;ZD 4522 Calcium;ZD 4522 Calcium Salt;BD-04;(E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrim idin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid, calcium salt (2:1);7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid;ZD4522;ROSUVASTATIN CA;Rosuvastatin Calium;Rosuvastain Calcium;DSSTox_CID_25928;DSSTox_RID_81229;DSSTox_GSID_45928;Tox21_111449;BC205450;calcium (E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate;Calcium;(E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-d;Calcium;(E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate;Rosuvastatin Calcium Tablets;Rosuvastatin hemicalcium;Rosuvastatin calcium salt;CRESTOR;ZD 4522, Calcium Salt;Rosuvastatin Calcium;ZD 4522;R0180;s2169;NSC-758930;SCHEMBL150740;(S-(R*,S*-(E)))-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)-5-PYRIMIDINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID, CALCIUM SALT;calcium bis[(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate];ZD-4522 (Calcium salt);SCHEMBL429217;ROSUVASTATIN CALCIUN;Rosuvastatin calcium;ROSUVASTATIN CALCIUM [ORANGE BOOK];KS-1109;NSC-747274;AKOS017343682;Suvikan;Monocalcium bis((3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methanesulfonyl (methyl) amino] pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate);Calcium, Rosuvastatin;DTXCID7025928;ROSUVASTATIN CALCIUM [JAN];(S-((R*,S*-(E)))-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, calcium salt (2:1);Q-201685;AS-12488;EZALLOR;calcium;(E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate;BCP04131;ZD4522 CALCIUM;ROSUVASTATIN CALCIUM SALT [MI];calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate;ROSUVASTATIN CALCIUM (USP-RS);NSC 758930;ROSUVASTATIN CALCIUM [MART.];EZALLOR SPRINKLE;Rovista;ROSUVASTATIN CALCIUM [USP-RS];Crestor (TN);ROSUVASTATIN CALCIUM (EP MONOGRAPH);(S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, calcium salt (2:1);NSC 747274;UNII-83MVU38M7Q;CHEMBL1744447;ZD 4522, calcium salt;BR164378;calcium bis((3R,5S,6E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-... |
| CAS号 | 147098-20-2 |
| 分子式 | C44H54CaF2N6O12S2 |
| 分子量 | 1001.14 |
| 产品描述 | 瑞舒伐他汀钙（标准品） Rosuvastatin (Calcium) (Standard) 是 Rosuvastatin (Calcium) 的分析标准品。本产品用于研究及分析应用。Rosuvastatin Calcium 是一种竞争性 HMG-CoA 还原酶 (HMGCR) 抑制剂，IC50 为11 nM。Rosuvastatin Calcium 有效阻断 hERG 电流，IC50 为 195 nM。Rosuvastatin Calcium 降低成熟 hERG 的表达以及热休克蛋白 70 (Hsp70) 与 hERG 蛋白的相互作用。Rosuvastatin Calcium 有效降低低密度脂蛋白 (LDL) 胆固醇，甘油三酯和 C- 反应蛋白水平。 |
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